| 2022-07-30 14:00:3530 July 2022 | Largs Thistle  | 1 - 1 |  Glenafton Athletic | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-08-06 14:00:216 August 2022 | Pollok  | 0 - 0 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-08-13 14:00:4813 August 2022 | Largs Thistle | 1 - 5 |  Kirkintilloch Rob Roy | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-08-20 14:00:4820 August 2022 | Vale of Leven  | 2 - 4 | Largs Thistle | South Challenge Cup | 2022-23 | N/A |
| 2022-08-27 14:30:2127 August 2022 | Craigmark Burtonians  | 4 - 2 | Largs Thistle | Scottish Junior Cup | 2022-23 | N/A |
| 2022-09-03 14:00:423 September 2022 | Largs Thistle | 2 - 1 |  Cumnock Juniors | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-09-17 14:00:3917 September 2022 | Hurlford Utd  | 2 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-09-24 14:00:0924 September 2022 | Irvine Meadow XI  | 1 - 1 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-10-01 14:00:281 October 2022 | Largs Thistle | 0 - 2 |  Kilwinning Rangers | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-10-08 14:00:468 October 2022 | Clydebank  | 3 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-10-15 14:00:4215 October 2022 | Beith Juniors  | 3 - 4 | Largs Thistle | South Challenge Cup | 2022-23 | N/A |
| 2022-10-22 14:00:1622 October 2022 | Ardeer Thistle  | 0 - 2 | Largs Thistle | West of Scotland Cup | 2022-23 | N/A |
| 2022-11-05 14:00:525 November 2022 | Largs Thistle | 1 - 0 |  Troon | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-11-09 19:30:019 November 2022 | Darvel  | 1 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-11-12 13:30:3712 November 2022 | Largs Thistle | 1 - 3 | Hurlford Utd | West of Scotland Cup | 2022-23 | N/A |
| 2022-11-19 14:00:3019 November 2022 | Clydebank | 4 - 0 | Largs Thistle | South Challenge Cup | 2022-23 | N/A |
| 2022-11-26 13:30:1926 November 2022 | Largs Thistle | 0 - 1 |  Cambuslang Rangers | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-12-03 13:30:193 December 2022 | Beith Juniors | 4 - 1 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2022-12-30 19:30:5430 December 2022 | Glenafton Athletic | 0 - 1 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-01-07 13:30:087 January 2023 | Cambuslang Rangers | 2 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-01-21 13:30:5921 January 2023 | Largs Thistle | 1 - 3 | Beith Juniors | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-01-25 19:30:3825 January 2023 | Auchinleck Talbot  | 3 - 0 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-01-28 14:00:3528 January 2023 | Cumnock Juniors | 0 - 1 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-02-03 19:30:043 February 2023 | Petershill  | 3 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-02-11 14:00:3311 February 2023 | Largs Thistle | 5 - 0 |  Arthurlie | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-02-18 14:00:4518 February 2023 | Largs Thistle | 1 - 2 | Clydebank | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-02-25 14:00:4725 February 2023 | Largs Thistle | 4 - 0 | Petershill | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-03-04 14:00:374 March 2023 | Arthurlie | 1 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-03-11 14:00:5811 March 2023 | Largs Thistle | 3 - 1 | Irvine Meadow XI | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-03-18 14:00:2918 March 2023 | Kirkintilloch Rob Roy | 14:00:29Postponed | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-03-24 19:30:5824 March 2023 | Troon | 1 - 2 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-04-01 14:00:051 April 2023 | Largs Thistle | 0 - 2 | Darvel | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-04-22 14:00:0422 April 2023 | Largs Thistle | 4 - 1 | Hurlford Utd | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-04-25 19:00:3825 April 2023 | Largs Thistle | 1 - 0 | Auchinleck Talbot | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-05-06 14:00:146 May 2023 | Kilwinning Rangers | 1 - 0 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-05-10 19:30:1910 May 2023 | Kirkintilloch Rob Roy | 0 - 1 | Largs Thistle | West of Scotland Premier Division | 2022-23 | N/A |
| 2023-05-13 14:00:4113 May 2023 | Largs Thistle | 5 - 1 | Pollok | West of Scotland Premier Division | 2022-23 | N/A |
